Undergraduate Degree

  • Haverford College , 1991 , Haverford , PA

Medical School

  • Mount Sinai Medical School , 1995 , New York , NY


  • Boston Children's Hospital , 1996 , Boston , MA


  • Boston Children's Hospital , 1998 , Boston , MA

Graduate Degree

  • Harvard School of Public Health , 2000 , Boston , MA


Hospital Medicine and Health Services Research
  • Boston Children's Hospital , 2000 , Boston , MA


Christopher P. Landrigan, MD, MPH is the Chief of General Pediatrics at Boston Children’s Hospital, Director of the Sleep and Patient Safety Program at Brigham and Women’s Hospital, and the William Berenberg Professor of Pediatrics at Harvard Medical School. He was a founding member of the Harvard Work Hours, Health, and Safety Group, and the founding chair of the Pediatric Research in Inpatient Settings (PRIS) Network, a collaboration of over 100 pediatric hospitals that conducts multi-center research and improvement projects.

Dr. Landrigan has led a series of major studies on the epidemiology of medical errors, and interventions designed to reduce their incidence. His most important work has been focused on developing reliable patient safety measurement tools, and improving the organization of residency programs and academic medical centers. His work on the relationship between resident work hours, sleep, and patient safety contributed to national changes in resident work hour standards. More recently, he led the development of I-PASS, a multi-faceted handoff and communication improvement program. He has authored over 150 publications in the medical literature, and has received numerous awards for his research, teaching, leadership, and innovation.


  • American Board of Pediatrics, General Pediatrics
  • American Board of Pediatrics, Pediatric Hospital Medicine


Publications powered by Harvard Catalyst Profiles

  1. Evaluation of an Educational Outreach and Audit and Feedback Program to Reduce Continuous Pulse Oximetry Use in Hospitalized Infants With Stable Bronchiolitis: A Nonrandomized Clinical Trial. JAMA Netw Open. 2021 Sep 01; 4(9):e2122826. View abstract
  2. Interns' perspectives on impacts of the COVID-19 pandemic on the medical school to residency transition. BMC Med Educ. 2021 Jun 07; 21(1):330. View abstract
  3. Extended Work Shifts and Neurobehavioral Performance in Resident-Physicians. Pediatrics. 2021 03; 147(3). View abstract
  4. A Changing Landscape: Exploring Resident Perspectives on Pursuing Pediatric Hospital Medicine Fellowships. Hosp Pediatr. 2021 Feb; 11(2):109-115. View abstract
  5. Barriers and Facilitators to Guideline-Adherent Pulse Oximetry Use in Bronchiolitis. J Hosp Med. 2021 01; 16(1):23-30. View abstract
  6. Association Between Parent Comfort With English and Adverse Events Among Hospitalized Children. JAMA Pediatr. 2020 12 01; 174(12):e203215. View abstract
  7. The Effect of Blue-Enriched Lighting on Medical Error Rate in a University Hospital ICU. Jt Comm J Qual Patient Saf. 2021 03; 47(3):165-175. View abstract
  8. Pediatric Resident Engagement With an Online Critical Care Curriculum During the Intensive Care Rotation. Pediatr Crit Care Med. 2020 11; 21(11):986-991. View abstract
  9. Validity of Continuous Pulse Oximetry Orders for Identification of Actual Monitoring Status in Bronchiolitis. J Hosp Med. 2020 11; 15(11):665-668. View abstract
  10. Association Between Bronchiolitis Patient Volume and Continuous Pulse Oximetry Monitoring in 25 Hospitals. J Hosp Med. 2020 11; 15(11):669-672. View abstract
  11. Patient Safety and Resident Schedules without 24-Hour Shifts. Reply. N Engl J Med. 2020 09 24; 383(13):1288. View abstract
  12. Effect on Patient Safety of a Resident Physician Schedule without 24-Hour Shifts. N Engl J Med. 2020 06 25; 382(26):2514-2523. View abstract
  13. I-PASS Mentored Implementation Handoff Curriculum: Frontline Provider Training Materials. MedEdPORTAL. 2020 06 22; 16:10912. View abstract
  14. Communicating Effectively With Hospitalized Patients and Families During the COVID-19 Pandemic. J Hosp Med. 2020 07 01; 15(7):440-442. View abstract
  15. The Elephant in the Hospital Room Charge. Pediatrics. 2020 06; 145(6). View abstract
  16. Prevalence of Continuous Pulse Oximetry Monitoring in Hospitalized Children With Bronchiolitis Not Requiring Supplemental Oxygen. JAMA. 2020 04 21; 323(15):1467-1477. View abstract
  17. The Association Between Resident Physician Work-Hour Regulations and Physician Safety and Health. Am J Med. 2020 07; 133(7):e343-e354. View abstract
  18. In Reply to Lawson. Acad Med. 2020 01; 95(1):11-12. View abstract
  19. Hidden health IT hazards: a qualitative analysis of clinically meaningful documentation discrepancies at transfer out of the pediatric intensive care unit. JAMIA Open. 2019 Oct; 2(3):392-398. View abstract
  20. Association of Pediatric Resident Physician Depression and Burnout With Harmful Medical Errors on Inpatient Services. Acad Med. 2019 08; 94(8):1150-1156. View abstract
  21. Effects on resident work hours, sleep duration, and work experience in a randomized order safety trial evaluating resident-physician schedules (ROSTERS). Sleep. 2019 08 01; 42(8). View abstract
  22. Patient Safety under Flexible and Standard Duty-Hour Rules. N Engl J Med. 2019 06 13; 380(24):2379-2380. View abstract
  23. Measuring overuse of continuous pulse oximetry in bronchiolitis and developing strategies for large-scale deimplementation: study protocol for a feasibility trial. Pilot Feasibility Stud. 2019; 5:68. View abstract
  24. Communication at Transitions of Care. Pediatr Clin North Am. 2019 08; 66(4):751-773. View abstract
  25. Design and recruitment of the randomized order safety trial evaluating resident-physician schedules (ROSTERS) study. Contemp Clin Trials. 2019 05; 80:22-33. View abstract
  26. I-PASS Mentored Implementation Handoff Curriculum: Champion Training Materials. MedEdPORTAL. 2019 01 10; 15:10794. View abstract
  27. "All the ward's a stage": a qualitative study of the experience of direct observation of handoffs. Adv Health Sci Educ Theory Pract. 2019 05; 24(2):301-315. View abstract
  28. Patient safety after implementation of a coproduced family centered communication programme: multicenter before and after intervention study. BMJ. 2018 12 05; 363:k4764. View abstract
  29. Racial, Ethnic, and Socioeconomic Disparities in Patient Safety Events for Hospitalized Children. Hosp Pediatr. 2019 01; 9(1):1-5. View abstract
  30. Developing Standardized "Receiver-Driven" Handoffs Between Referring Providers and the Emergency Department: Results of a Multidisciplinary Needs Assessment. Jt Comm J Qual Patient Saf. 2018 12; 44(12):719-730. View abstract
  31. I-PASS Mentored Implementation Handoff Curriculum: Implementation Guide and Resources. MedEdPORTAL. 2018 08 03; 14:10736. View abstract
  32. I-PASS Handoff Program: Use of a Campaign to Effect Transformational Change. Pediatr Qual Saf. 2018 Jul-Aug; 3(4):e088. View abstract
  33. Adverse Events in Hospitalized Pediatric Patients. Pediatrics. 2018 08; 142(2). View abstract
  34. Cutting Children's Health Care Costs. Pediatrics. 2018 08; 142(2). View abstract
  35. Effect of Increased Inpatient Attending Physician Supervision on Medical Errors, Patient Safety, and Resident Education: A Randomized Clinical Trial. JAMA Intern Med. 2018 07 01; 178(7):952-959. View abstract
  36. Using a Pediatric Trigger Tool to Estimate Total Harm Burden Hospital-acquired Conditions Represent. Pediatr Qual Saf. 2018 May-Jun; 3(3):e081. View abstract
  37. Comparison of Empiric Antibiotics for Acute Osteomyelitis in Children. Hosp Pediatr. 2018 05; 8(5):280-287. View abstract
  38. A Comparison of Resident Self-Perception and Pediatric Hospitalist Perceptions of the Supervisory Needs of New Interns. Hosp Pediatr. 2018 04; 8(4):214-219. View abstract
  39. Stress From Uncertainty and Resilience Among Depressed and Burned Out Residents: A Cross-Sectional Study. Acad Pediatr. 2018 08; 18(6):698-704. View abstract
  40. Engaging Families as True Partners During Hospitalization. J Hosp Med. 2018 05 01; 13(5):358-360. View abstract
  41. Development, Implementation, and Assessment of the Intensive Clinical Orientation for Residents (ICOR) Curriculum: A Pilot Intervention to Improve Intern Clinical Preparedness. Acad Pediatr. 2018 03; 18(2):140-144. View abstract
  42. Parent-Provider Miscommunications in Hospitalized Children. Hosp Pediatr. 2017 09; 7(9):505-515. View abstract
  43. Effects of the I-PASS Nursing Handoff Bundle on communication quality and workflow. BMJ Qual Saf. 2017 Dec; 26(12):949-957. View abstract
  44. Simulation of a Novel Schedule for Intensivist Staffing to Improve Continuity of Patient Care and Reduce Physician Burnout. Crit Care Med. 2017 Jul; 45(7):1138-1144. View abstract
  45. Resident Experiences With Implementation of the I-PASS Handoff Bundle. J Grad Med Educ. 2017 Jun; 9(3):313-320. View abstract
  46. Integrating Research, Quality Improvement, and Medical Education for Better Handoffs and Safer Care: Disseminating, Adapting, and Implementing the I-PASS Program. Jt Comm J Qual Patient Saf. 2017 07; 43(7):319-329. View abstract
  47. Inpatient Hospital Factors and Resident Time With Patients and Families. Pediatrics. 2017 May; 139(5). View abstract
  48. Families as Partners in Hospital Error and Adverse Event Surveillance. JAMA Pediatr. 2017 04 01; 171(4):372-381. View abstract
  49. Parent and Provider Experience and Shared Understanding After a Family-Centered Nighttime Communication Intervention. Acad Pediatr. 2017 May - Jun; 17(4):389-402. View abstract
  50. Applying mathematical models to predict resident physician performance and alertness on traditional and novel work schedules. BMC Med Educ. 2016 Sep 13; 16(1):239. View abstract
  51. Performance of the Global Assessment of Pediatric Patient Safety (GAPPS) Tool. Pediatrics. 2016 06; 137(6). View abstract
  52. Communication and Shared Understanding Between Parents and Resident-Physicians at Night. Hosp Pediatr. 2016 Jun; 6(6):319-29. View abstract
  53. Reliability of Verbal Handoff Assessment and Handoff Quality Before and After Implementation of a Resident Handoff Bundle. Acad Pediatr. 2016 08; 16(6):524-31. View abstract
  54. Parent-Reported Errors and Adverse Events in Hospitalized Children. JAMA Pediatr. 2016 Apr; 170(4):e154608. View abstract
  55. The Creation of Standard-Setting Videos to Support Faculty Observations of Learner Performance and Entrustment Decisions. Acad Med. 2016 Feb; 91(2):204-9. View abstract
  56. Alarm fatigue: Clearing the air. J Hosp Med. 2016 Feb; 11(2):153-4. View abstract
  57. Intern and Resident Workflow Patterns on Pediatric Inpatient Units: A Multicenter Time-Motion Study. JAMA Pediatr. 2015 Dec; 169(12):1175-7. View abstract
  58. Physician and Nurse Nighttime Communication and Parents' Hospital Experience. Pediatrics. 2015 Nov; 136(5):e1249-58. View abstract
  59. The authors reply "Variation in printed handoff documents: Results and recommendations from a multicenter needs assessment". J Hosp Med. 2016 Jan; 11(1):81-2. View abstract
  60. Graduated Driver-Licensing: The Authors Reply. Health Aff (Millwood). 2015 Sep; 34(9):1610. View abstract
  61. Teen Crashes Declined After Massachusetts Raised Penalties For Graduated Licensing Law Restricting Night Driving. Health Aff (Millwood). 2015 Jun; 34(6):963-70. View abstract
  62. Variation in printed handoff documents: Results and recommendations from a multicenter needs assessment. J Hosp Med. 2015 Aug; 10(8):517-24. View abstract
  63. A trigger tool to detect harm in pediatric inpatient settings. Pediatrics. 2015 Jun; 135(6):1036-42. View abstract
  64. Crying wolf: False alarms and patient safety. J Hosp Med. 2015 Jun; 10(6):409-10. View abstract
  65. Changes in medical errors with a handoff program. N Engl J Med. 2015 01 29; 372(5):490-1. View abstract
  66. Changes in medical errors after implementation of a handoff program. N Engl J Med. 2014 Nov 06; 371(19):1803-12. View abstract
  67. Decreasing handoff-related care failures in children's hospitals. Pediatrics. 2014 Aug; 134(2):e572-9. View abstract
  68. Development, implementation, and dissemination of the I-PASS handoff curriculum: A multisite educational intervention to improve patient handoffs. Acad Med. 2014 Jun; 89(6):876-84. View abstract
  69. Preventing health care-associated harm in children. JAMA. 2014 May 07; 311(17):1731-2. View abstract
  70. Placing faculty development front and center in a multisite educational initiative: lessons from the I-PASS Handoff study. Acad Pediatr. 2014 May-Jun; 14(3):221-4. View abstract
  71. Safer hours for doctors and improved safety for patients. Med J Aust. 2014 Apr 21; 200(7):396-8. View abstract
  72. Rates of medical errors and preventable adverse events among hospitalized children following implementation of a resident handoff bundle. JAMA. 2013 Dec 04; 310(21):2262-70. View abstract
  73. Quality improvement research in pediatric hospital medicine and the role of the Pediatric Research in Inpatient Settings (PRIS) network. Acad Pediatr. 2013 Nov-Dec; 13(6 Suppl):S54-60. View abstract
  74. Closing the gap: a needs assessment of medical students and handoff training. J Pediatr. 2013 May; 162(5):887-8.e1. View abstract
  75. New questions on the road to safer health care. Pediatrics. 2013 May; 131(5):e1621-2. View abstract
  76. Answering questions on call: pediatric resident physicians' use of handoffs and other resources. J Hosp Med. 2013 Jun; 8(6):328-33. View abstract
  77. Fatigue optimization scheduling in graduate medical education: reducing fatigue and improving patient safety. J Grad Med Educ. 2013 Mar; 5(1):107-11. View abstract
  78. Making residency work hour rules work. J Law Med Ethics. 2013; 41(1):310-4. View abstract
  79. (Mis) perceptions and interactions of sleep specialists and generalists: obstacles to referrals to sleep specialists and the multidisciplinary team management of sleep disorders. J Clin Sleep Med. 2012 Dec 15; 8(6):633-42. View abstract
  80. Sleep science, schedules, and safety in hospitals: challenges and solutions for pediatric providers. Pediatr Clin North Am. 2012 Dec; 59(6):1317-28. View abstract
  81. Development of the Pediatric Research in Inpatient Settings (PRIS) Network: lessons learned. J Hosp Med. 2012 Oct; 7(8):661-4. View abstract
  82. Pediatric hospitalists: coming of age in 2012. Arch Pediatr Adolesc Med. 2012 Aug; 166(8):696-9. View abstract
  83. Pediatric residents' perspectives on reducing work hours and lengthening residency: a national survey. Pediatrics. 2012 Jul; 130(1):99-107. View abstract
  84. Better rested, but more stressed? Evidence of the effects of resident work hour restrictions. Acad Pediatr. 2012 Jul-Aug; 12(4):335-43. View abstract
  85. Surgeon fatigue: a prospective analysis of the incidence, risk, and intervals of predicted fatigue-related impairment in residents. Arch Surg. 2012 May; 147(5):430-5. View abstract
  86. I-pass, a mnemonic to standardize verbal handoffs. Pediatrics. 2012 Feb; 129(2):201-4. View abstract
  87. Sleep disorders, health, and safety in police officers. JAMA. 2011 Dec 21; 306(23):2567-78. View abstract
  88. Effects of a night-team system on resident sleep and work hours. Pediatrics. 2011 Dec; 128(6):1142-7. View abstract
  89. Healthcare provider working conditions and well-being: sharing international lessons to improve patient safety. J Pediatr (Rio J). 2011 Nov-Dec; 87(6):463-5. View abstract
  90. The effect of physician sleep deprivation on patient safety in perinatal-neonatal medicine. Am J Perinatol. 2012 Jan; 29(1):43-8. View abstract
  91. Implementing the 2009 Institute of Medicine recommendations on resident physician work hours, supervision, and safety. Nat Sci Sleep. 2011; 3:47-85. View abstract
  92. Unit-based care teams and the frequency and quality of physician-nurse communications. Arch Pediatr Adolesc Med. 2011 May; 165(5):424-8. View abstract
  93. Temporal trends in rates of patient harm resulting from medical care. N Engl J Med. 2010 Nov 25; 363(22):2124-34. View abstract
  94. Does simulator-based clinical performance correlate with actual hospital behavior? The effect of extended work hours on patient care provided by medical interns. Acad Med. 2010 Oct; 85(10):1583-8. View abstract
  95. Establishing a multisite education and research project requires leadership, expertise, collaboration, and an important aim. Pediatrics. 2010 Oct; 126(4):619-22. View abstract
  96. Performance characteristics of a methodology to quantify adverse events over time in hospitalized patients. Health Serv Res. 2011 Apr; 46(2):654-78. View abstract
  97. Effects of reducing or eliminating resident work shifts over 16 hours: a systematic review. Sleep. 2010 08; 33(8):1043-53. View abstract
  98. Family-centered rounds on pediatric wards: a PRIS network survey of US and Canadian hospitalists. Pediatrics. 2010 Jul; 126(1):37-43. View abstract
  99. US public opinion regarding proposed limits on resident physician work hours. BMC Med. 2010 Jun 01; 8:33. View abstract
  100. Resident sleep deprivation and critical care: the unintended consequences of inaction. Crit Care Med. 2010 Mar; 38(3):980-1. View abstract
  101. Risks of complications by attending physicians after performing nighttime procedures. JAMA. 2009 Oct 14; 302(14):1565-72. View abstract
  102. Reforming procedural skills training for pediatric residents: a randomized, interventional trial. Pediatrics. 2009 Aug; 124(2):610-9. View abstract
  103. Cappuccio response to correspondence. QJM. 2009 May; 102(5):363-4. View abstract
  104. Neurobehavioral, health, and safety consequences associated with shift work in safety-sensitive professions. Curr Neurol Neurosci Rep. 2009 Mar; 9(2):155-64. View abstract
  105. Implementing a 48 h EWTD-compliant rota for junior doctors in the UK does not compromise patients' safety: assessor-blind pilot comparison. QJM. 2009 Apr; 102(4):271-82. View abstract
  106. Driving drowsy. J Clin Sleep Med. 2008 Dec 15; 4(6):536-7. View abstract
  107. Building physician work hour regulations from first principles and best evidence. JAMA. 2008 Sep 10; 300(10):1197-9. View abstract
  108. Effects of the accreditation council for graduate medical education duty hour limits on sleep, work hours, and safety. Pediatrics. 2008 Aug; 122(2):250-8. View abstract
  109. Variation in pediatric hospitalists' use of proven and unproven therapies: a study from the Pediatric Research in Inpatient Settings (PRIS) network. J Hosp Med. 2008 Jul; 3(4):292-8. View abstract
  110. Improving sleep hygiene. Arch Intern Med. 2008 Jun 09; 168(11):1229-30; author reply 1230. View abstract
  111. Improving nurse working conditions: towards safer models of hospital care. J Hosp Med. 2008 May; 3(3):181-3. View abstract
  112. Effect of computer order entry on prevention of serious medication errors in hospitalized children. Pediatrics. 2008 Mar; 121(3):e421-7. View abstract
  113. Rates of medication errors among depressed and burnt out residents: prospective cohort study. BMJ. 2008 Mar 01; 336(7642):488-91. View abstract
  114. Effects of health care provider work hours and sleep deprivation on safety and performance. Jt Comm J Qual Patient Saf. 2007 Nov; 33(11 Suppl):7-18. View abstract
  115. Effective implementation of work-hour limits and systemic improvements. Jt Comm J Qual Patient Saf. 2007 Nov; 33(11 Suppl):19-29. View abstract
  116. Assessing procedural skills training in pediatric residency programs. Pediatrics. 2007 Oct; 120(4):715-22. View abstract
  117. Impact of a hospitalist system on length of stay and cost for children with common conditions. Pediatrics. 2007 Aug; 120(2):267-74. View abstract
  118. Medication errors related to computerized order entry for children. Pediatrics. 2006 Nov; 118(5):1872-9. View abstract
  119. Interns' compliance with accreditation council for graduate medical education work-hour limits. JAMA. 2006 Sep 06; 296(9):1063-70. View abstract
  120. Variations in management of common inpatient pediatric illnesses: hospitalists and community pediatricians. Pediatrics. 2006 Aug; 118(2):441-7. View abstract
  121. When policy meets physiology: the challenge of reducing resident work hours. Clin Orthop Relat Res. 2006 Aug; 449:116-27. View abstract
  122. Pediatric hospitalists: a systematic review of the literature. Pediatrics. 2006 May; 117(5):1736-44. View abstract
  123. Pediatric hospitalists: report of a leadership conference. Pediatrics. 2006 Apr; 117(4):1122-30. View abstract
  124. Recovery from medical errors: the critical care nursing safety net. Jt Comm J Qual Patient Saf. 2006 Feb; 32(2):63-72. View abstract
  125. A shift for the better. Chest. 2005 Dec; 128(6):3787-8. View abstract
  126. Sliding down the Bell curve: effects of 24-hour work shifts on physicians' cognition and performance. Sleep. 2005 Nov; 28(11):1351-3. View abstract
  127. Preventable adverse events in infants hospitalized with bronchiolitis. Pediatrics. 2005 Sep; 116(3):603-8. View abstract
  128. The Critical Care Safety Study: The incidence and nature of adverse events and serious medical errors in intensive care. Crit Care Med. 2005 Aug; 33(8):1694-700. View abstract
  129. The safety of inpatient pediatrics: preventing medical errors and injuries among hospitalized children. Pediatr Clin North Am. 2005 Aug; 52(4):979-93, vii. View abstract
  130. Effect of intern's consecutive work hours on safety, medical education and professionalism. Crit Care. 2005 Oct 05; 9(5):528-30; author reply 528-30. View abstract
  131. Effect of reducing interns' weekly work hours on sleep and attentional failures. N Engl J Med. 2004 Oct 28; 351(18):1829-37. View abstract
  132. Effect of reducing interns' work hours on serious medical errors in intensive care units. N Engl J Med. 2004 Oct 28; 351(18):1838-48. View abstract
  133. Complications in infants hospitalized for bronchiolitis or respiratory syncytial virus pneumonia. J Pediatr. 2003 Nov; 143(5 Suppl):S142-9. View abstract
  134. Prioritizing strategies for preventing medication errors and adverse drug events in pediatric inpatients. Pediatrics. 2003 Apr; 111(4 Pt 1):722-9. View abstract
  135. Outbreaks of typhoid fever in the United States, 1960-99. Epidemiol Infect. 2003 Feb; 130(1):13-21. View abstract
  136. Senior resident autonomy in a pediatric hospitalist system. Arch Pediatr Adolesc Med. 2003 Feb; 157(2):206-7. View abstract
  137. The impact of climate change on child health. Ambul Pediatr. 2003 Jan-Feb; 3(1):44-52. View abstract
  138. Impact of a health maintenance organization hospitalist system in academic pediatrics. Pediatrics. 2002 Oct; 110(4):720-8. View abstract
  139. Effect of a pediatric hospitalist system on housestaff education and experience. Arch Pediatr Adolesc Med. 2002 Sep; 156(9):877-83. View abstract
  140. Rotavirus cerebellitis? Clin Infect Dis. 2002 Jan 01; 34(1):130. View abstract
  141. Pediatric hospitalists in Canada and the United States: a survey of pediatric academic department chairs. Ambul Pediatr. 2001 Nov-Dec; 1(6):338-9. View abstract
  142. Pediatric hospitalists: what do we know, and where do we go from here? Ambul Pediatr. 2001 Nov-Dec; 1(6):340-5. View abstract
  143. Preventable deaths and injuries during magnetic resonance imaging. N Engl J Med. 2001 Sep 27; 345(13):1000-1. View abstract
  144. Medication errors and adverse drug events in pediatric inpatients. JAMA. 2001 Apr 25; 285(16):2114-20. View abstract
  145. Age and secular trends in bone lead levels in middle-aged and elderly men: three-year longitudinal follow-up in the Normative Aging Study. Am J Epidemiol. 1997 Oct 01; 146(7):586-91. View abstract